David GutierrezOne of the greatest controversies in oncology may have been resolved: Researchers may have discovered the reason that research into the effectiveness of high-dose vitamin C as a cancer treatment has been so mixed.When taken orally, massive quantities of vitamin C are either broken down or excreted unused by the body. In contrast, intravenous administration of vitamin C produces blood levels 100 to 500 times higher than oral administration.This could explain why many clinical trials on vitamin C and cancer — most of which have used oral administration — failed to support the results